Letrozole – 2.5mg (30 tabs)

Letrozole 2.5 mg is an oral medication containing 2.5 mg of letrozole per tablet. Letrozole is classified as a non-steroidal aromatase inhibitor and is commonly prescribed in the management of hormone-sensitive conditions.

Active Ingredient

Letrozole works by inhibiting the aromatase enzyme, which is responsible for converting androgens into estrogen. By reducing estrogen production, it lowers circulating estrogen levels in the body.

Composition

Each tablet typically contains:

• Letrozole – 2.5 mg

• Pharmaceutical excipients such as fillers, binders, and coating agents

Inactive ingredients vary depending on the manufacturer.

Mechanism of Action

Letrozole selectively blocks the aromatase enzyme, decreasing estrogen synthesis in peripheral tissues. This reduction in estrogen is particularly important in hormone receptor–positive breast cancer, where estrogen can stimulate tumor growth.

Medical Uses

Letrozole is commonly prescribed for the treatment of hormone receptor–positive breast cancer in postmenopausal women. It may be used as initial therapy, after surgery, or following treatment with other hormonal agents. In certain cases, it may also be used in fertility treatment under medical supervision.

Pharmacological Characteristics

Letrozole is well absorbed after oral administration and has a relatively long elimination half-life, supporting once-daily dosing in clinical practice. It is primarily metabolized in the liver.