Raloxifene – 60mg (30 tabs)

Raloxifene 60 mg is an oral medication containing 60 mg of raloxifene hydrochloride per tablet. Raloxifene is classified as a Selective Estrogen Receptor Modulator (SERM) and is prescribed for specific hormone-related conditions.

Active Ingredient

Raloxifene Hydrochloride selectively binds to estrogen receptors. Depending on the target tissue, it can act as either an estrogen receptor agonist or antagonist. It primarily blocks estrogen effects in breast tissue while exerting estrogen-like effects in bone.

Composition

Each tablet typically contains:

• Raloxifene Hydrochloride – equivalent to 60 mg raloxifene

• Pharmaceutical excipients such as fillers, binders, and coating agents

Inactive ingredients vary depending on the manufacturer.

Mechanism of Action

Raloxifene modulates estrogen receptor activity. In bone tissue, it mimics estrogen’s beneficial effects by reducing bone resorption and helping maintain bone mineral density. In breast tissue, it acts as an antagonist, reducing estrogen stimulation.

Medical Uses

Raloxifene is commonly prescribed for the prevention and treatment of osteoporosis in postmenopausal women. It may also be used to reduce the risk of invasive breast cancer in certain high-risk postmenopausal women, as determined by a healthcare professional.

Pharmacological Characteristics

Raloxifene is absorbed after oral administration and undergoes extensive hepatic metabolism. It has a relatively long half-life due to enterohepatic circulation, allowing for once-daily dosing.