Pregnyl – 5000 IU

Pregnyl 5000 IU is an injectable preparation containing 5000 International Units of Human Chorionic Gonadotropin (HCG) per vial. It is supplied as a lyophilized (freeze-dried) powder that must be reconstituted with sterile bacteriostatic water or sterile water before administration. Pregnyl is widely used in clinical practice for reproductive and hormonal therapies.

Active Ingredient

Human Chorionic Gonadotropin (HCG) is a naturally occurring glycoprotein hormone. In males, it mimics luteinizing hormone (LH) to stimulate testosterone production. In females, it supports ovulation and early pregnancy by promoting follicular development and corpus luteum function.

Composition

Each vial typically contains:

• Human Chorionic Gonadotropin – 5000 IU

• Stabilizing agents such as mannitol

• Supplied as a sterile, freeze-dried powder for reconstitution

The solvent for reconstitution may be included or provided separately, depending on the manufacturer.

Mechanism of Action

HCG functions by mimicking LH, stimulating Leydig cells in the testes to produce testosterone in males. In females, it triggers ovulation by stimulating the release of the egg from ovarian follicles. Its activity helps regulate hormonal balance and reproductive function.

Medical Uses

Pregnyl is prescribed for:

• Male hypogonadism to restore testosterone production

• Inducing ovulation in women undergoing fertility treatments

• Supporting early pregnancy in cases of luteal insufficiency

All uses should be under the guidance of a qualified healthcare professional.

Pharmacological Characteristics

Following injection, HCG is gradually absorbed and exhibits prolonged biological activity, supporting hormone production over several days. Its half-life allows for effective dosing schedules without daily administration.