Tamoxifen (Nolvadex) – 10mg (50 tabs)

Tamoxifen (Nolvadex) 10 mg is an oral medication containing 10 mg of tamoxifen citrate per tablet. Tamoxifen is classified as a Selective Estrogen Receptor Modulator (SERM) and is widely used in the management of certain hormone-related conditions.

Active Ingredient

Tamoxifen Citrate selectively binds to estrogen receptors in various tissues. In breast tissue, it primarily acts as an estrogen receptor antagonist, helping to block the effects of estrogen.

Composition

Each tablet typically contains:

• Tamoxifen Citrate (equivalent to 10 mg tamoxifen)

• Pharmaceutical excipients such as fillers, binders, and coating agents

Inactive ingredients vary depending on the manufacturer.

Mechanism of Action

Tamoxifen competes with estrogen for binding to estrogen receptors. In estrogen-sensitive tissues such as breast tissue, it reduces estrogen stimulation. In other tissues, including bone and uterine tissue, it may exert partial estrogen-like activity.

Medical Uses

Tamoxifen is commonly prescribed for the treatment of estrogen receptor–positive (ER+) breast cancer and for reducing the risk of recurrence. It may also be used in certain preventive settings for individuals at elevated risk. Treatment duration and dosing are determined by a healthcare professional.

Pharmacological Characteristics

Tamoxifen is absorbed after oral administration and metabolized in the liver into active metabolites. It has a relatively long elimination half-life, contributing to sustained therapeutic action.